Thursday, February 16, 2017

week 2 Decode me!!


 
AUGUGGACCCAAGCCACUUGCAGAUUCAACUAG

4 comments:

  1. I believe you were suppose to do this in DNA not mRNA.

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  2. sorry for the late response and thanks for the correction here you go
    AUGAGGTCCCTTGCCTCAAGCTATAACTTC

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  3. Mercedes, the correction is right, but you should have included your decode if you weren't planning to return and continue the conversation. This is similar to the problem with the student comment left on your blog post. More information was needed for your response. If you translated the RNA, you should have noticed problems beyond the missing DNA.

    Daisy, you have a few problems with your post. Mercedes was correct that you should have posted the DNA instead of the RNA. You've posted the DNA in your comment, but I don't think your process was correct for this. It would have helped if you had posted your correct sentence so I could work with it to see what you did wrong. I'll work through what I know and perhaps that will help you figure out your errors.

    Let's start with the RNA first. This should be an easy decode, since it is just one step away from your sentence. You have the start codon in place, so the translation process should start right after that. Unfortunately, when I do the translation, the sentence doesn't make sense, which suggests that you made some other change to the RNA... or perhaps your sentence doesn't start right after the start codon? Without your actual sentence, I can't tell.

    RNA: AUG UGG ACC CAA GCC ACU UGC AGA UUC AAC UAG
    (start) To monster dream good pizza after class for anthropology (stop)

    Looking at your DNA above and comparing that to your RNA gives us this:

    DNA: AUG AGG TCC CTT GCC TCA AGC TAT AAC TTC
    RNA: AUG UGG ACC CAA GCC ACU UGC AGA UUC AAC UAG

    First of all, the DNA is shorter but that is because you left off the stop codon. Otherwise, what pops out to me is that you only reverse-transcribed the A's and T's. You left the C's and G's alone. That doesn't work, as you needed to reverse transcribe all the bases to create the DNA molecule.

    Remember that what we are trying to do here is replicate the process of protein synthesis in the cell. If you have read through this process in the textbook, it should be familiar to you. The enzyme responsible for transcribing the DNA transcribes ALL the bases, not just the adenine and thymine.

    One other relatively minor issue is the missing random bases at the beginning and end of your DNA, but the core problem here is that the RNA doesn't seem to produce a working sentence, which suggests something was wrong in how you reverse-translated your sentence into RNA.

    Without your sentence, I can't go any further than this. If you want to post your sentence, I can take a look at it and see if I can figure out the problem. Just email me if you do this so I will know to return and review it.

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